yes, but anything less that 15 grams, causes mutations in the dna structure
*Lead has direct toxic effects on spermatogenesis, resulting in a decreased sperm count and an increase in the number of abnormal sperm*
perhaps thats the reason the mutation of dna rather than lead poisoning in the brain
Lead affects the central nervous system by multiple different mechanisms, most of which are unexplored. In the brain, lead is known to alter the function of cellular calcium and inactivate the blood-brain barrier. These alterations result in leakage of proteinaceous fluid and brain edema, which affects all parts of the CNS, predominantly the cerebellum and the occipital lobes. Lead-induced cerebral edema is manifested initially by headaches, clumsiness, vertigo, and ataxia, followed by seizures, coma, mortality, or recovery with permanent neurologic loss. Lead also impairs the function of several protein kinases and neurotransmitters. In the peripheral nervous system, lead poisoning causes segmental demyelination of motor neurons and destruction of Schwann cells, resulting in motor neuron dysfunction.
Other effects
Lead has negative effects on the reproductive system, causing low sperm count and abnormal sperm morphology in men and infertility, menstrual irregularity, spontaneous abortion, and stillbirths in women.
In children, lead impairs the release of human growth hormone and insulin growth factor and interferes with skeletal calcium and cyclic adenosine monophosphate (cAMP) functions, resulting in abnormalities of bone growth. Chronic exposure to lead also may result in reduced thyroid function. Rarely, acute lead poisoning results in hepatitis, pancreatitis, or cardiac dysfunction
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