I've never had positive results from St John's Wort. At best it did fuck all, and at worst it can interfere with certain medications like hormonal BC. The only OTC supplement that helped me was 5-HTP, and that was after a LOT of tweaking. The original dosage on the bottle gave me *serious* rage issues - to the point that I wouldn't leave the house because I would just seethe with rage after 15 seconds. My lovely, retired, super sweet neighbors who would do anything for me and worry about me? I wanted to drive my car through their door just for waving. Once I realized it, I got off of them. I felt better after a few days, and then started lowering the dosage. I found that one pill, once a day, of the lowest dosage you can get (50mg) is enough for me when I start a new cycle of depression.
I was insanely low in vitamin D at the time too, so as someone who can't be out in the sun long enough for my body to produce it, I take a small supplement for that off and on. I will go about a month or so on the supplement, and about a month or so off. I also take iron for chronic anemia, that no one can figure out why I have. After having health insurance again for the first time in years, I just had a blood test for my thyroid so I can get back on meds for it. However, I was ON all of those things during my nervous breakdown.
What helped me the most when I was in my worst cycle of depression ever was simply waiting for it to start to lift, then journaling. I was so bad I couldn't function - I didn't even do dishes for 6 weeks, I couldn't even muster up the energy to *watch TV* - I just sat down on the couch and stared at the wall for hours on end. I barely showered. I was as bad as the most disgusting moo we've read about on here. Once it started to lift and I had the ability to do things again, I was so desperate, I contacted a psychic. She told me to look into a book called "The Artist's Way" and to at least do the main exercise in the book - morning pages. It was extremely difficult to start, but I gradually figured quite a few things out about myself through them, and it was free. I made more progress in those two months than I did in nine months of going to a "therapist" (who actually left me feeling MORE suicidal than when I went in, then told me there was nothing else she could do). I have severe nerve damage in my writing hand from self-mutilation, and so it was painful to hand write those pages every morning. I took my time and did it anyway. I was unemployed, lost all my scholarships, and had been suspended from school. I had nothing to do anyway, so I wrote. I eventually found online journals (penzu and 750words) where I could do them without fear of anyone reading them, and much less painfully. While that helped bring me out of the worst of it and realize a lot of things, I was still mired in a pervasive, low-grade depression, and it was very slow to change anything about my life.
Eventually I started meditating, which also helped. I realized more things about myself that I wanted to change, and I've slowly been making those changes. Since I do believe in a "higher power," I asked that higher power for help to change, in my own eclectic, weird way. If you don't, then ask *yourself" to change, in whatever way makes sense to you. Once I started doing that, serendipitous coincidences started to randomly happen. Maybe I was subconsiously looking for them, maybe it was that "higher power" giving me the a-okay sign. I don't know.
This past year, I was told two other books to read that would help me out:
Wishcraft and
Write it Down, Make it Happen. Wishcraft is available for free on on the web. I found the other in a used book store. While there are a LOT of things I roll my eyes about in both of them - they have both already been incredible for me. Not in a hocus-pocus "The secret" kind of way - although they both go down that road - but in making me realize and focus on what I really want out of life, and what would really make me happy. I take what's useful and get a good laugh out of the rest (or a good eye roll). (Warning: Wishcraft's first chapter will make you rage as it's all about teh speyshulness of all the sneauxflaekes. If you chose to read the book, just ignore it and get past it. I just roll my eyes and skip it until I come to something useful, like the exercises in the book. Write it Down has one particularly embarrassing "example" of someone following the steps, again, just ignore it or just laugh at her like I did.)
I still have much smaller bouts of depression. I still have negative thoughts about myself and slip into funks. I am not cured, and I'm not sure I ever will be. But I'm actually making plans for the future and seeing a future beyond the next year - something that I never did for over half my life. When I was 11, I stopped "seeing" myself past the age of 18. I was convinced I would be dead. From the time I was 18 to the time I was 28, I never planned for the future. Despite enrolling in college, I never thought I would live to graduate. I tried to commit suicide and I self mutilated multiple times. I never thought any further ahead than one semester or one year. My grades are a trainwreck, and an even worse one is my employment record. I'm 31 years old, and because of how severe my depression was for years, I've never been in a relationship. Hell, I've never even been on a date (not that I particularly want to with anyone around here, but still). I've got a long way to go before I'll ever feel remotely "normal". But I have hope now where I didn't have it before. I see a future for myself, and I have long term goals for the first time in 20 years. What worked for me may not work for you. Everyone is different. Everyone is inspired by or dragged down by different things. Everyone finds insight in different ways. But it CAN be done. I'm doing it. You can do it too, I promise.
"Selfishness is not living as one wishes to live, it is asking others to live as one wishes to live." - Oscar Wilde